RE:fine Drugs is an interactive dashboard of drug repositioning opportunities by "drug-gene-disease" triads, using the methods described in Nature Biotech 2012 (GWAS) and Nature Biotech 2015 (PheWAS). It currently contains 60,911 opportunities covering 916 drugs, 567 genes and 1770 diseases.

Please start your search by entering a drug name (e.g. Zidovudine), a disease name (e.g. Alzheimer's Disease), or a gene symbol (e.g. IL2RB).

Getting Started

Info
Drug
Registered Indication
P-Value Range

to
P-Value Adjusted Range
to
Odds Ratio
0
117.5
Study
New Indication
Found Indication in DrugBank
Number of Medline Abstracts
0
1000
Number in Clinical Trial Registry
0
10000
Repurposing Potential
SNP
Gene Symbol
Action
Info Drug Registered Indication P-Value P-Value Adjusted Odds Ratio Study New Indication Drug Bank Indication # of Medline Abstracts # of Clinical Trial Registry Potential SNP Gene Action

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Drug Repurposing Legend